Adverse effects of intraportal chemotherapy on natural killer cell activity in colorectal cancer patients

Author(s):  
Mohammad Rafique ◽  
Wataru Adachi ◽  
Shoichiro Koike ◽  
Shoji Kajikawa ◽  
Kazuyuki Yazawa ◽  
...  
1987 ◽  
Vol 24 (1) ◽  
pp. 86-91 ◽  
Author(s):  
Lucio Tentori ◽  
Maria Pia Fuggetta ◽  
Stefania D'Atri ◽  
Angelo Aquino ◽  
Corrado Nunziata ◽  
...  

1985 ◽  
Vol 95 (5) ◽  
pp. 588???594 ◽  
Author(s):  
Stimson P. Schantz ◽  
Marvin M. Romsdahl ◽  
Kenji Nishioka ◽  
George F. Babcock ◽  
Helmuth Goepfert

2004 ◽  
Vol 14 (4) ◽  
pp. 589-594 ◽  
Author(s):  
W.-S. Ahn ◽  
D.-J. Kim ◽  
G.-T. Chae ◽  
J.-M. Lee ◽  
S.-M. Bae ◽  
...  

A mushroom extract, Agaricus blazei Murill Kyowa (ABMK), has been reported to possess antimutagenic and antitumor effects. Here, we investigate the beneficial effects of ABMK consumption on immunological status and qualities of life in cancer patients undergoing chemotherapy. One hundred cervical, ovarian, and endometrial cancer patients were treated either with carboplatin (300 mg/m2) plus VP16 (etoposide, 100 mg/m2) or with carboplatin (300 mg/m2) plus taxol (175 mg/m2) every 3 weeks for at least three cycles with or without oral consumption of ABMK. We observed that natural killer cell activity was significantly higher in ABMK-treated group (ANOVA, n = 39, P < 0.002) as compared with nontreated placebo group (n = 61). However, no significant difference in lymphokine-activated killer and monocyte activities was observed in a manner similar to the count of specific immune cell populations between ABMK-treated and nontreated groups. However, chemotherapy-associated side effects such as appetite, alopecia, emotional stability, and general weakness were all improved by ABMK treatment. Taken together, this suggests that ABMK treatment might be beneficial for gynecological cancer patients undergoing chemotherapy.


1987 ◽  
Vol 5 (4) ◽  
pp. 285-291 ◽  
Author(s):  
B. K. Choe ◽  
P. Frost ◽  
M. K. Morrison ◽  
N. R. Rose

1991 ◽  
Vol 63 (6) ◽  
pp. 1010-1014 ◽  
Author(s):  
ML Villa ◽  
E Ferrario ◽  
E Bergamasco ◽  
F Bozzetti ◽  
L Cozzaglio ◽  
...  

1996 ◽  
Vol 39 (4) ◽  
pp. 429-434 ◽  
Author(s):  
Alejandro Espí ◽  
Javier Arenas ◽  
Eduardo García-Granero ◽  
Elena Martí ◽  
Salvador Lledó

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